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5HT1A Receptor Rabbit pAb (bs-1124R)  
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產品編號 bs-1124R
英文名稱 5HT1A Receptor Rabbit pAb
中文名稱 5-羥色胺受體1A抗體
別    名 5HT1A Receptor; HTR1A; 5-HTR1A; 5 HT 1A; 5 HT receptor 1A; 5 HT1A; 5 HT1A receptor; 5 hydroxytryptamine(serotonin) receptor 1A; 5 hydroxytryptamine(serotonin) receptor 1A G protein coupled; 5 hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; 5-hydroxytryptamine receptor 1A; 5HT 1A; 5HT 1A receptor; 5HT receptor 1A; 5HT1a; 5HT1A_HUMAN; ADRB2RL1; ADRBRL1; G 21; G protein coupled receptor; G-21; Gpcr 18; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; PFMCD; Serotonin 1A receptor; Serotonin 5HT1A receptor; Serotonin receptor 1A;  
Specific References  (3)     |     bs-1124R has been referenced in 3 publications.
[IF=5.62] Zhou, Q. G., et al. "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert?/? mice."Translational Psychiatry 6.6 (2016): e836.  WB ;  Mouse.  
[IF=4.17] Yeh, C-B., et al. "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." Osteoporosis International (2016): 1-10.  IHC-F ;  Rat.  
[IF=2.72] Lan Yao. et al. Armillaria mellea fermentation liquor ameliorates p-chlorophenylalanine-induced insomnia associated with the modulation of serotonergic system and gut microbiota in rats. 2022 Jan 05  WB,IHC ;  Rat.  
研究領域 腫瘤  免疫學  神經生物學  信號轉導  轉錄調節因子  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5-HTR1A: 301-400/422 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012].

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.

SWISS:
P08908

Gene ID:
3350

Database links:

Entrez Gene: 487230 Dog

Entrez Gene: 3350 Human

Entrez Gene: 15550 Mouse

Entrez Gene: 24473 Rat

Omim: 109760 Human

SwissProt: Q6XXX9 Dog

SwissProt: Q0EAB6 Horse

SwissProt: P08908 Human

SwissProt: Q64264 Mouse

SwissProt: P19327 Rat

Unigene: 247940 Human

Unigene: 4716 Mouse

Unigene: 44486 Rat



產品圖片
Sample: Lane 1: Mouse Brain Lysates Lane 2: Mouse Cerebellum Lysates Lane 3: Mouse Lymph Lysates Lane 4: Rat Brain Lysates Lane 5: Rat Cerebellum Lysates Primary: Anti-5HT1A Receptor (bs-1124R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46kDa Observed band size: 46kDa
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