麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
狠狠婷婷,91久久精品国产免费一区,国产精品福利一区
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Podoplanin Rabbit pAb (bs-1048R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號 bs-1048R
英文名稱 Podoplanin Rabbit pAb
中文名稱 平足蛋白/淋巴管內(nèi)皮細(xì)胞蛋白抗體
別    名 PDPN_HUMAN; DPN; GP36; Aggrus; Glycoprotein 36(Gp36); PA2.26 antigen; T1-alpha; T1A; 29kDa cytosolic podoplanin intracellular domain; PICD; PSEC0003; PSEC0025;  
Specific References  (8)     |     bs-1048R has been referenced in 8 publications.
[IF=8.213] Yiqi Yanget al. Bioprinting of an osteocyte network for biomimetic mineralization. Biofabrication . 2020 Jul 29;12(4):045013.  ICC ;  mouse.  
[IF=5.391] Choy MV et al. Can we enhance osteoporotic metaphyseal fracture healing through enhancing ultrastructural and functional changes of osteocytes in cortical bone with low-magnitude high-frequency vibration?. FASEB J. 2020 Jan 21.  IHC-P ;  Rat.  
[IF=4.202] Majumder et al. A practical and sensitive method of quantitating lymphangiogenesis in vivo. (2013) Lab.Inves. 93:779-91  IF(IHC-F) ;  Mouse.  
[IF=3.829] Umezawa K et al. Phospholipase?Cε?plays?a?crucial?role?in?neutrophilic?inflammation?accompanying?acute?lunginjury?through?augmentation?of?CXC?chemokine?production?from?alveolar?epithelial cells. Respir Res. 2019 Jan 11;20(1):9.  WB&ICF ;  Mouse.  
[IF=3.622] Zhu Xiaoying. et al. LRRC superfamily expression in stromal cells predicts the clinical prognosis and platinum resistance of ovarian cancer. BMC MED GENOMICS. 2023 Dec;16(1):1-16  IHC ;  Human.  
[IF=2.751] Ziqian Liu. et al. Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis. EXP THER MED. 2022 Oct;24(4):1-12  IHC ;  Rat.  
[IF=1.487] Yuefeng Gaoet al. Vitamin E promotes ovine Sertoli cell proliferation by regulation of genes associated with cell division and the cell cycle. Anim Biotechnol . 2020 Jul 2;1-9.  WB ;  sheep.  
[IF=1.48] Gao, Peng, et al. "Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling." Molecular Medicine Reports.  other ;  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  免疫學(xué)  淋巴細(xì)胞  內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15 kDa
檢測分子量 36-40
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Podoplanin: 91-166/166 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function:
May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

Subcellular Location:
Membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, microvillus membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane; Single-pass type I membrane protein. Note=Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.

Tissue Specificity:
Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.

Post-translational modifications:
Extensively O-glycosylated. Contains sialic acid residues. O-glycosylation is necessary for platelet aggregation activity.
The N-terminus is blocked.

Similarity:
Belongs to the podoplanin family.

SWISS:
Q62011

Gene ID:
14726

Database links:

Entrez Gene: 10630 Human

Entrez Gene: 14726 Mouse

Entrez Gene: 54320 Rat

Omim: 608863 Human

SwissProt: Q86YL7 Human

SwissProt: Q62011 Mouse

SwissProt: Q64294 Rat

Unigene: 468675 Human

Unigene: 2976 Mouse

Unigene: 794 Rat



Podoplanin Protein是一種腎小球足狀突細(xì)胞膜粘蛋白,目前已成為一種新的淋巴管內(nèi)皮標(biāo)記物蛋白,在少數(shù)小靜脈上也有表達(dá)。
podoplanin Protein是淋巴管內(nèi)皮高度敏感且特異性的標(biāo)記物,作為腫瘤細(xì)胞的血小板聚集介導(dǎo)因子而發(fā)揮作用,能促進(jìn)腫瘤細(xì)胞遷移及增加腫瘤細(xì)胞侵襲力。
產(chǎn)品圖片
Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti- Podoplanin (bs-1048R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 15 kD Observed band size: 37 kD
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Podoplanin) Polyclonal Antibody, Unconjugated (bs-1048R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Tissue/cell: mouse kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Podoplanin Protein/gp36 Polyclonal Antibody, Unconjugated(bs-1048R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 中文一区在线观看 | 国产精品美女久久久浪潮软件 | 少妇精品视频一区二区免费看 | 亚洲av日韩av不卡在线观看 | 扒开双腿疯狂进出爽爽爽水视频 | 亚洲一级色片 | 久久人人槡人妻人人玩夜色AV | 久久国产精品色av免费观看 | 免费看无码自慰一区二区 | 在线精品国产一区二区三区 | 情欲综合网| 中文字幕一级毛片视频 | 少妇愉情理仑片高潮 | 欧美小视频在线观看 | 一区二区高清在线 | 精品国产99高清一区二区三区 | 九九精品成人免费国产片 | 色婷婷av777 性xxxxfreexxxxx喷水欧美 | 中文字幕一区在线观看视频 | 久久久久无码国产精品一区乞丐 | 日本免费色视频 | 成年男女免费视频在线观看不卡 | 成年人国产在线观看 | 特级毛片爽WWW免费版 | 肉大捧一进一出免费视频 | 黄色av大片在线观看 | 亚洲精品无码一区二区 | 狠狠躁日日躁狂躁夜夜躁av | 中文字幕精品—区二区四季 | 日韩中字幕 | 女人张开腿让男桶喷水高潮 | 亚洲AV无码一区东京热蜜芽 | 国产精品视频二区三区 | 中国A级毛片免费观看 | 国色天香在线视频www | 91视频进入 | 欧美激情天堂 | 亚洲国产亚洲国产亚洲 | 无码精品A片一区二区 | www.47久久青青 | 91久久久久久久久 |