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Thymosin Alpha-1 Rabbit pAb (bs-0226R)  
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產(chǎn)品編號 bs-0226R
英文名稱 Thymosin Alpha-1 Rabbit pAb
中文名稱 胸腺肽α1抗體
別    名 Prothymosin alpha(gene sequence 28); Prothymosin alpha; Prothymosin alpha like 1 protein; Thymalfasin; Thymosin alpha 1 acetate; Thymosin alpha 1; Thymosin alpha; TMSA; PTMA; PTMA_HUMAN.  
Specific References  (1)     |     bs-0226R has been referenced in 1 publications.
[IF=2.42] Shao, Congwen, et al. "Thymosin alpha-1-transformed< i> Bifidobacterium promotes T cell proliferation and maturation in mice by oral administration." International immunopharmacology (2013).  WB ;  
研究領(lǐng)域 腫瘤  免疫學(xué)  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Rat (predicted: Mouse,Cow)
產(chǎn)品應(yīng)用 ICC/IF=1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Thymosin Alpha-1: 2-29/111 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin alpha. A peptide containing 28 amino acid residues, named thymosin alpha 1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and in vivo test systems. Thymosin alpha 1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin alpha 1.

Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.

Subcellular Location:
Nucleus.

Post-translational modifications:
Covalently linked to a small RNA of about 20 nucleotides.

Similarity:
Belongs to the pro/parathymosin family.

SWISS:
P06454

Gene ID:
5757

Database links:

Entrez Gene: 5757 Human

Omim: 188390 Human

SwissProt: P06454 Human

Unigene: 459927 Human

Unigene: 708083 Human



胸腺素α-1;胸腺肽
產(chǎn)品圖片
MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (Thymosin Alpha-1) polyclonal Antibody, Unconjugated (bs-0026R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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