麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
超碰网站在线,精品少妇XXXX,欧美美女久久
首頁 > 產品中心 > 一抗 > 產品信息
NRF1 Rabbit pAb (bs-1342R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-1342R
英文名稱 NRF1 Rabbit pAb
中文名稱 核呼吸因子-1抗體
別    名 erythroid derived 2; like 1; Locus control region factor 1; Locus control region-factor 1; NF-E2-related factor 1; NF2L1_HUMAN; NFE2 related factor 1; NFE2-related factor 1; NFE2L1; NRF-1; NRF 1; Nuclear factor; Nuclear factor erythroid 2-related factor 1; Nuclear factor erythroid derived 2 like 1; TCF-11; TCF11; Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR F1; Transcription factor LCR-F1.  
Specific References  (4)     |     bs-1342R has been referenced in 4 publications.
[IF=6.117] Yue Shen. et al. Lycopene prevents Di-(2-ethylhexyl) phthalate-induced mitophagy and oxidative stress in mice heart via modulating mitochondrial homeostasis. J NUTR BIOCHEM. 2023 May;115:109285  WB ;  Mouse.  
[IF=3.974] Ning X et al.Ambient PM2. 5 causes lung injuries and coupled energy metabolic disorder. (2018) Ecotoxicol. Environ. Saf. 170  WB ;  Mouse.  
[IF=3.95] Yan, Wei, et al. "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." Environmental Research 138 (2015): 416-424.  WB ;  Rat.  
[IF=3.76] Qin, Guohua, et al. "Sulfur dioxide inhalation stimulated mitochondrial biogenesis in rat brains." Toxicology 300.1 (2012): 67-74.  WB ;  Rat.  
研究領域 染色質和核信號  轉錄調節因子  合成與降解  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1ug/Test,ICC/IF=1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55 kDa
檢測分子量
細胞定位 細胞核 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRF1: 51-180/503 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

Function:
Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

Subunit:
Homodimer. Binds DNA as a dimer. Interacts with PPRC1.

Subcellular Location:
Nucleus

Tissue Specificity:
Ubiquitously expressed with strongest expression in skeletal muscle.

Post-translational modifications:
Phosphorylation enhances DNA binding.

Similarity:
Belongs to the NRF1/Ewg family.

SWISS:
Q16656

Gene ID:
4899

Database links:

Entrez Gene: 4899 Human

Omim: 600879 Human

SwissProt: Q16656 Human

Unigene: 654363 Human

 



NRF-1是核基因編碼且影響mtDNA的另一重要因子, 他控制著線粒體電子傳遞鏈的一些蛋白質的合成。
產品圖片
Sample: Lane1:Heart (Mouse) Lysate at 30 ug Lane2:Mucle (Mouse) Lysate at 30 ug Primary: Anti- NRF-1/TCF11 (bs-1342R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
Paraformaldehyde-fixed, paraffin embedded (Human colon cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NRF1) Polyclonal Antibody, Unconjugated (bs-1342R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-NRF-1 Polyclonal Antibody, Unconjugated(bs-1342R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (NRF1) polyclonal Antibody, Unconjugated (bs-1342R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
Blank control:Jurkat. Primary Antibody (green line): Rabbit Anti-Iba1 antibody (bs-1342R) Dilution: 1ug/Test; Secondary Antibody : Goat anti-rabbit IgG-FITC Dilution: 0.5ug/Test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at -20℃.The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国内不卡的一区二区三区中文字幕 | 中文一区在线观看 | 中文字幕一区二区三区精华液 | 日本免费一区二区三区日本 | 麻豆视频免费看 | 欧美国产激情一区二区三区蜜月 | 国产小受被做到哭咬床单GV | 少妇翘臀亚洲精品av图片 | 欧美专区日韩视频人妻 | 911影院在线观看网站 | 初尝黑人嗷嗷叫中文字幕 | 欧美精品粉嫩高潮一区二区 | 美女AV一区二区三区 | 玩护士睡老师勾搭女下属 | 国产在线青青草 | 网站av免费 | 少妇作爱bbbb免费看 | 日韩人妻无码精品专区综合网 | 91网页视频入?在线?看 | 97资源站在线视频 | 欧美日韩国产的视频图片 | 欧美日韩免费在线观看 | 全部免费的a毛片在线看 | 亚洲第1页 | 两根一起进三P免费视频 | 最新版天堂资源中文官网 | 国产一二三四五区 | 久久dvd | 西西人体www大胆高清仙踪林 | 成人夜间福利 | 欧美激烈精交gif动态图 | 免费在线黄 | 亚洲福利国产精品17p | 欧美日韩五区 | 极品美女高潮呻吟国产剧情91 | 一本色道久久综合狠狠躁 | 丰满少妇无码在线观看 | 我要看一级黄色 | 丰满少妇被猛烈高清播放 | 天天爱天天做天天爽夜夜揉 | 色翁荡息又大又硬又粗又爽 |