麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美综合视频在线,欧美一区自拍,无码专区天天躁天天躁在线
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
SUR1 Rabbit pAb (bs-3641R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-3641R
英文名稱 SUR1 Rabbit pAb
中文名稱 磺酰脲類藥物受體1抗體
別    名 ABC36; Abcc8; ATP binding cassette sub family C(CFTR/MRP) member 8; ATP binding cassette transporter sub family C member 8(1); HHF1; HRINS; MRP8; PHHI; Sulfonylurea receptor 1; SUR.  
Specific References  (1)     |     bs-3641R has been referenced in 1 publications.
[IF=0.91] Horii K et al. ATP-dependent potassium channels contribute to motor regulation of esophageal striated muscle in rats. J Vet Med Sci. 2019 Jul 9.  IHC-P ;  Rat.  
研究領(lǐng)域 免疫學(xué)  細(xì)胞膜受體  藥物及化合物  糖尿病  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 175 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUR1: 301-400/1581 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SUR1 is a member of ATP binding cassette super family. SUR receptor confers the sensitivity of Kir6.2 to ATP/ADP sensitivity and to pharmacological agents such as sulfonylurea and diazoxide that close or open the KATP channels. The persistent heyperinsulinimic hypoglycemia in infancy (PHHI) is familial disorder due to defect in negative feed back in response to low glucose levels. SUR1 was mapped on chromosome 11p14-15.1, the same location where the gene for PHHI is located. It has been shown that the expression of Kir6.2 and SUR1 are regulated by glucose levels and the actives of glucogon like peptide receptor 1. Abnormal insulin secretion in PHHI appears to be caused by mutations in the SUR gene.

Subunit:
Interacts with KCNJ11.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.

SWISS:
Q09428

Gene ID:
6833

Database links:

Entrez Gene: 6833 Human

Entrez Gene: 20927 Mouse

Entrez Gene: 25559 Rat

Omim: 600509 Human

SwissProt: Q09428 Human

SwissProt: Q09429 Rat

Unigene: 54470 Human

Unigene: 11187 Rat



胰島β細(xì)胞膜含有磺酰脲受體及與之相偶聯(lián)的ATP敏感的鉀通道Ik(ATP),以及電壓依賴性的鈣通道。當(dāng)磺酰脲類藥物與其受體相結(jié)合后,可阻滯Ik(ATP)而阻鉀外流,致使細(xì)胞膜去極化,增強(qiáng)電壓依賴性鈣通道開放,胞外鈣內(nèi)流。胞內(nèi)游離鈣濃度增加后,觸發(fā)胞吐作用及胰島素的釋放。
產(chǎn)品圖片
Sample: Hippocampus (Mouse) Lysate at 40 ug Primary: Anti-SUR1 (bs-3641R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 175 kD Observed band size: 175 kD
Sample: Lane 1: Cerebrum (Mouse) Lysate at 40 ug Lane 2: Pancreas (Mouse) Lysate at 40 ug Lane 3: Stomach (Mouse) Lysate at 40 ug Lane 4: Cerebrum (Rat) Lysate at 40 ug Lane 5: SH-SY5Y (Human) Cell Lysate at 30 ug Primary: Anti-SUR1 (bs-22836R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 177 kD Observed band size: 180 kD
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 乱码国产丰满人妻WWW | 国产精品永久免费嫩草研究院 | 情侣做性视频在线播放 | 香蕉久久国产 | 在线视频日韩一区 | 特级少妇| 精品国产乱码久久久久久密桃99 | 国产精品黄网在线播放 | 国产精品扒开腿做爽爽的视频 | 一本一本久久A久久综合精品 | 久久久88 | 国产精品一品二区三区四区18 | 亚洲人成人伊人成综合网无码 | 国产精品久久久久久麻豆一区胖胖 | 日韩无套无码精品 | 亚洲国产精品高清久久久 | 国产精品自在线拍国产手机版 | 国产精品大片免费观看 | 18成人免费观看视频 | 天堂蜜桃91精品 | 日韩精品无码一区二区 | 一级毛片私人影院 | 亚洲AV成人片无码WWW | 国产人碰人摸人爱视频 | 91免费影视 | 中文字幕一区二区人妻 | 狠狠躁天天躁夜夜躁婷婷老牛影视 | 日韩欧美国产aⅴ另类 | 免费成人在线播放 | 在线视频日韩欧美国产 | 亚洲网站h| 国产熟妇疯狂4P交在线播放 | 中文久久久久 | 免费va视频| 国产精品18久久久久久首页狼 | 国产丰满果冻videossex | 国产艳妇AV在线 | 91高清免费在线观看 | 秋霞在线观看片无码免费 | 国产高清在线视频观看 | 色在线看|