麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
2222eeee成人天堂,久久久av免费,亚洲一卡2卡3卡4卡精品
首頁 > 產品中心 > 一抗 > 產品信息
PGP9.5 Rabbit pAb (bs-3806R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-3806R
英文名稱 PGP9.5 Rabbit pAb
中文名稱 神經細胞胞漿蛋白9.5/蛋白基因產物9.5抗體
別    名 Gracile axonal dystrophy; Neuron cytoplasmic protein 9.5; Park 5; Park5; Parkinson Disease 5; PGP 9.5; PGP95; Protein gene product 9.5; Ubiquitin C terminal esterase L1; Ubiquitin C terminal hydrolase(neuron specific); Ubiquitin C terminal hydrolase; Ubiquitin carboxyl terminal esterase L1; Ubiquitin carboxyl terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin thioesterase L1; Ubiquitin thiolesterase; Ubiquitin thiolesterase L1; UCH L1; UCH-L1; UCHL1; UCHL1_HUMAN.  
Specific References  (7)     |     bs-3806R has been referenced in 7 publications.
[IF=7.81] Deng, Shou‐Long, et al. "Melatonin promotes development of haploid germ cells from early developing spermatogenic cells of Suffolk sheep under in vitro condition." Journal of Pineal Research (2016).  Sheep.  
[IF=5.295] Ko-Chao Lee. et al. Use of iTRAQ-based quantitative proteomic identification of CHGA and UCHL1 correlated with lymph node metastasis in colorectal carcinoma. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023 May;:  IHC,WB ;  Human.  
[IF=5.23] Zheng, Liming, et al. "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." Scientific Reports 6 (2016): 37414.  IF(IHC-P) ;  Goat.  
[IF=3.12] Zheng, Liming, et al. "CD49f promotes proliferation of male dairy goat germline stem cells." Cell Proliferation (2016).  Goat.  
[IF=1.75] Li, Bo, et al. "Bovine male germline stem-like cells cultured in serum-and feeder-free medium." Cytotechnology: 1-13.  IHC-P ;  Bovine.  
[IF=1.638] Zhu H et al. p53 inhibits the proliferation of male germline stem cells from dairy goat cultured on poly‐L‐lysine. Reprod Domest Anim. 2020 Jan 27.  ICF ;  dairy goat.  
[IF=0.72] Lei, Qi-jing, et al. Establishment and characterization of immortalized bovine male germline stem cell line. Journal of Integrative Agriculture 2017, 16(11): 2547–2557.  WB ;  Bovine.  
研究領域 細胞生物  神經生物學  細胞類型標志物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat,Cow (predicted: Pig,GuineaPig,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PGP95: 35-140/223 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 catalyzes the hydrolysis of ubiquitin carboxy-terminal thiolesters to form ubiquitin and a thiol; may play a role in neuropathic pain [RGD].
Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.

Function:
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Subcellular Location:
Cytoplasm. Endoplasmic reticulum membrane. About 30% of total UCHL1 is associated with membranes in brain.

Tissue Specificity:
Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.

Post-translational modifications:
O-glycosylated.

DISEASE:
Defects in UCHL1 are the cause of Parkinson disease type 5 (PARK5) [MIM:613643]; also known as Parkinson disease autosomal dominant 5. PARK5 is a complex neurodegenerative disorder with manifestations ranging from typical Parkinson disease to dementia with Lewy bodies. Clinical features include parkinsonian symptoms (resting tremor, rigidity, postural instability and bradykinesia), dementia, diffuse Lewy body pathology, autonomic dysfunction, hallucinations and paranoia.

Similarity:
Belongs to the peptidase C12 family.

SWISS:
P09936

Gene ID:
7345

Database links:

Entrez Gene: 7345 Human

Entrez Gene: 22223 Mouse

Entrez Gene: 396637 Pig

Entrez Gene: 29545 Rat

Entrez Gene: 101117250 Sheep

Entrez Gene: 325119 Zebrafish

Omim: 191342 Human

SwissProt: P09936 Human

SwissProt: Q9R0P9 Mouse

SwissProt: Q6SEG5 Pig

SwissProt: Q00981 Rat

Unigene: 518731 Human

Unigene: 29807 Mouse

Unigene: 107213 Rat



該抗原是一種神經特異性蛋白,廣泛分布于中樞與外周神經系統的神經元和神經纖維、神經內分泌細胞、腎小管段、睪丸精原細胞、Leydig細胞、卵細胞以及妊娠與非妊娠黃體內的某些細胞。用于標記神經元,對研究幾種人慢性神經變性性疾病中廣泛存在的細胞包涵體特征較有意義。
產品圖片
Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (PGP9.5) Polyclonal Antibody, Unconjugated (bs-3806R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 香蕉视频在线网站 | 99精品大学生啪啪自拍 | 久久精品影视免费国产大片 | 亚洲中文字幕无码超碰 | 99久久综合精品五月天 | 久久久青 | 国产ts人妖系列高潮 | 日本孕妇高潮孕交视频 | 久久成人国产 | 在线一区二区三区精品 | 亚洲小说图片 | 麻花豆传的最新一期内容是 | 精品视频国产亚洲 | 91网站在线观看免费 | 免费在线观看成年人视频 | ririsao亚洲国产中文 | 特级毛片在线看 | 亚洲人www | 最新中文字幕一区二区三区 | 78m-78模成视频在线 | 久久妇女高潮几次MBA | 国产精品久久久久7777婷婷 | 特级丰满少妇一级aaaa爱毛片 | 欧美一级特黄a大片 | 亚洲国产长腿丝袜AV天堂 | 欧洲性XXXX免费视频在线观看 | 十八禁视频在线观看免费无码无遮挡骂过 | 日韩一区二区三区四 | 成人免费精品网站在线观看影片 | 免费毛片全部不收费的 | 在线观看av黄色 | 欧美寡妇XXXX黑人猛交 | 欧美视频一区在线 | 久久久久久久国产毛片 | 亚洲第三色 | 啪视频免费 | 美女午夜福利4K视频在线观看 | 天天人人干 | 一本一道久久久久久久久 | 一本大道香蕉大在线中文 | 午夜性做爰A片免费看 |