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SLC39A7 Rabbit pAb (bs-2391R)  
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產品編號 bs-2391R
英文名稱 SLC39A7 Rabbit pAb
中文名稱 轉運蛋白家族39成員7抗體
別    名 D6S115E; D6S2244E; H2 KE4; Histidine rich membrane protein Ke4; Histidine-rich membrane protein Ke4; HKE4; HLA class II region expressed gene KE4; KE4; Ke4 gene mouse, human homolog of; Really interesting new gene 5 protein; RING5; S39A7_HUMAN; SLC39A7; Solute carrier family 39(zinc transporter), member 7; Solute carrier family 39 member 7; solute carrier family 39 zinc transporter member 7; Zinc transporter SLC39A7; ZIP7.  
研究領域 腫瘤  細胞生物  信號轉導  轉運蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC39A7: 201-300/469 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Zinc is an essential cofactor for more than 50 classes of enzymes and is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, plus the control of gene transcription, growth, development, and differentiation. Zinc cannot passively diffuse across cell membranes and requires specific transporters, such as SLC39A7, to enter the cytosol from both the extracellular environment and from intracellular storage compartments.

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Tissue Specificity:
Major expression in placenta, lung, kidney and pancreas.

Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.

SWISS:
Q92504

Gene ID:
7922

Database links:

Entrez Gene: 7922 Human

Entrez Gene: 14977 Mouse

Entrez Gene: 294281 Rat

Omim: 601416 Human

SwissProt: Q92504 Human

SwissProt: Q31125 Mouse

Unigene: 631995 Human

Unigene: 18556 Mouse



產品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-C39A7 (bs-2391R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-SLC39A7 (bs-2391R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD
Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC39A7) Polyclonal Antibody, Unconjugated (bs-2391R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC39A7) Polyclonal Antibody, Unconjugated (bs-2391R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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