麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
看黄A大片爽爽影院免费无码,日韩国产在线播放,韩国三级激情吃奶
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
CYP2E1 Rabbit pAb (bs-4562R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-4562R
英文名稱 CYP2E1 Rabbit pAb
中文名稱 細(xì)胞色素P450ⅡE1抗體
別    名 4-nitrophenol 2-hydroxylase; CP2E1_HUMAN; CPE 1; CPE1; CYP2E; CYP2E1; CYP2E1; CYPIIE1; Cytochrome P450 2E1; cytochrome P450 family 2 subfamily E polypeptide 1; Cytochrome P450 isozyme 3A; Cytochrome P450 LM3A; Cytochrome P450 subfamily IIE(ethanol inducible) polypeptide 1; Cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450, subfamily IIE(ethanol-inducible), polypeptide 1; Cytochrome P450, subfamily IIE; Cytochrome P450-ALC; Cytochrome P450-J; Cytochrome P450RLM6; EC 1.14.13.-; EC 1.14.13.n7; Ethanol inducible p450; Ethanol inducible p450; Ethanol-inducible P450; flavoprotein-linked monooxygenase; MGC133529; microsomal monooxygenase; OTTHUMP00000020813; OTTHUMP00000046571; P450 ALC; P450 J; P450-J; P450C2E; P450C2E; P450J; P450RLM6; xenobiotic monooxygenase.  
Specific References  (8)     |     bs-4562R has been referenced in 8 publications.
[IF=4.784] Wang C et al. A novel acidic polysaccharide from the residue of Panax notoginseng and its hepatoprotective effect on alcoholic liver damage in mice. Int J Biol Macromol. 2020 Feb 6;149:1084-1097.  WB&IHF ;  Mouse.  
[IF=4.505] Wang H et al. Regulatory T cells suppress excessive lipid accumulation in alcoholic liver disease. J Lipid Res. 2019 Feb 21.  IHC-P ;  Mouse.  
[IF=4.427] Xie XL et al. PCB52 induces hepatotoxicity in male offspring through aggravating loss of clearance capacity and activating the apoptosis: Sex-biased effects on rats. Chemosphere. 2019 Jul;227:389-400.  WB ;  Rat.  
[IF=4.271] Biao Li. et al. 20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway. TOXICOL LETT. 2023 Jan;373:1  WB ;  Mouse.  
[IF=3.66] Iwao, Yasuhito, et al. "Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis." World Journal of Hepatology 9.32 (2017): 1227.  IHC-P ;  Pig.  
[IF=1.994] YING-HAO HAN. et al. Peroxiredoxin II Inhibits Alcohol-induced Apoptosis in L02 Hepatocytes Through AKT/β-Catenin Signaling Pathway. Anticancer Res. 2020 Aug;40(8):4491-4504  WB ;  Human.  
[IF=0.5] Shanshan Qi. et al. The hepatoprotective effect of Sophora viciifolia fruit extract against acetaminophen-induced liver injury in mice. J APPL BIOMED. 2023 May 18  IHC ;  Mouse.  
[IF=0] Iwao et al. Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis. (2017) World.J.Hepatol. 9:1227-1238  IHC-P ;  Human,Porcine.  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  脂蛋白  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 57 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYP2E1: 401-493/493 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and biosynthesis. Cytochrome P450 2E1 is induced by ethanol, diabetes and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, and exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Function:
Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Similarity:
Belongs to the cytochrome P450 family.

SWISS:
P05181

Gene ID:
1571

Database links:

Entrez Gene: 1571 Human

Entrez Gene: 13106 Mouse

Entrez Gene: 25086 Rat

Omim: 124040 Human

SwissProt: P05181 Human

SwissProt: Q05421 Mouse

SwissProt: P08682 Rabbit

SwissProt: P05182 Rat

Unigene: 12907 Human

Unigene: 21758 Mouse

Unigene: 1372 Rat



細(xì)胞色素P450 2E1(CYP2E1)可被乙醇等化合物誘導(dǎo), 參與多種前致癌物(N-亞硝胺、苯胺、氯乙烯、氨基甲酸乙酯)的代謝活化,誘發(fā)腫瘤的發(fā)生。
產(chǎn)品圖片
Sample: HepG2(Human) Cell Lysate at 30 ug Primary: Anti-CYP2E1 (bs-4562R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-CYP2E1 (bs-4562R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti-CYP2E1 (bs-4562R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CYP2E1 Polyclonal Antibody, Unconjugated(bs-4562R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Blank control:U937. Primary Antibody (green line): Rabbit Anti-CYP2E1 antibody (bs-4562R) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 0.1% PBST for 20 min at room temperature. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 强壮公弄得小薇高潮 | 高清一区二区视频 | 亚洲av日韩av永久无码不卡 | 三级成网站 | 亚洲国产精品日韩AV专区 | 最新中文字幕在线 | 老师穿超短包臀裙办公室爆乳 | 国产视频观看 | 久久久SS麻豆欧美国产日韩 | 欧一区二区三区 | 无码精品视频一区二区三区 | 亚洲成av人综合在线观看 | 久久精品一区二区三区国产主播 | 完美世界免费完整观看 | 操操操插插插 | 91超碰caoporm国产香蕉 | 国产在线高清理伦片a | 日韩第一视频 | 7777日本精品一区二区三区 | 欧美黄色网 | 成人免费精品网站在线观看影片 | 亚州性无码不卡免费视频 | 1000部啪啪未满十八勿入不卡 | 嗯好大好爽高潮了av大片 | JAPANESE强制高潮 | 欧美美女一区二区 | 国产精品无码AV天天爽播放器 | 欧美日韩激情一区二区 | 久久久1| 91制片在线观看 | 福利在线免费 | 大青草久久久蜜臀av久久 | 黄色一级毛片免费看 | 西西人体www大胆高清仙踪林 | 无线乱码一二三区免费看 | 5x社区在线视频免费播放 | 果冻传媒2021精品一区 | 97黑人性色浪潮91久久 | 欧美综合亚洲 | 久草视频免费在线播放 | 国产亚洲欧美另类在线第1页 |