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ADORA2B Rabbit pAb (bs-5900R)  
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產品編號 bs-5900R
英文名稱 ADORA2B Rabbit pAb
中文名稱 腺苷A2b受體/神經生長因子1受體抗體
別    名 Adenosine A2b Receptor; adora 2; adora 2b; ADORA2; ADORA2B; HGNC:264; Netrin 1 receptor; AA2BR_HUMAN.  
Specific References  (3)     |     bs-5900R has been referenced in 3 publications.
[IF=14.903] Gaona Shi. et al. Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells. ACTA PHARM SIN B. 2023 Apr;:  WB ;  Mouse.  
[IF=4.848] Alina V. Meyer. et al. Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity. Front Oncol. 2020; 10: 554883  FC ;  Mouse.  
[IF=3.061] Shi L et al. Adenosine Interaction with Adenosine Receptor A2a Promotes Gastric Cancer Metastasis by Enhancing PI3K–AKT–mTOR Signaling. Mol Biol Cell. 2019 Jul 24:mbcE19030136.  WB,IHC&ICF ;  Human.  
研究領域 腫瘤  心血管  免疫學  染色質和核信號  信號轉導  G蛋白偶聯受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADORA2B: 101-200/332 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].

Function:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P29275

Gene ID:
136

Database links:

Entrez Gene: 136 Human

Omim: 600446 Human

SwissProt: P29275 Human

Unigene: 167046 Human



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with ADORA2B polyclonal antibody, unconjugated (bs-5900R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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