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FbxL4 Rabbit pAb (bs-13166R)  
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產品編號 bs-13166R
英文名稱 FbxL4 Rabbit pAb
中文名稱 F-box富含亮氨酸重復蛋白4抗體
別    名 F box and leucine rich repeat protein 4; F box protein FBL4/FBL5; F box/LRR repeat protein 4; F-box and leucine-rich repeat protein 4; F-box protein FBL 4; F-box protein FBL4/FBL5; F-box/LRR-repeat protein 4; FBL 4; FBL 5; FBL4; FBL5; Fbxl4; FBXL4_HUMAN.  
研究領域 細胞生物  細胞周期蛋白  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Rat (predicted: Mouse,Sheep,Cow,Chicken)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 70 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FbxL4/FBL4: 15-100/621 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats. [provided by RefSeq, Jul 2008].

Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle.

Similarity:
Contains 1 F-box domain.
Contains 9 LRR (leucine-rich) repeats.

SWISS:
Q9UKA2

Gene ID:
26235

Database links:

Entrez Gene: 26235 Human

Entrez Gene: 269514 Mouse

Entrez Gene: 100156082 Pig

Entrez Gene: 535452 Cow

Omim: 605654 Human

SwissProt: Q0VD31 Cow

SwissProt: Q9UKA2 Human

SwissProt: Q8BH70 Mouse

Unigene: 536850 Human

Unigene: 40708 Mouse



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FbxL4) Polyclonal Antibody, Unconjugated (bs-13166R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FbxL4) Polyclonal Antibody, Unconjugated (bs-13166R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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