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IFI44L Rabbit pAb (bs-15551R)  
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產品編號 bs-15551R
英文名稱 IFI44L Rabbit pAb
中文名稱 干擾素誘導蛋白44樣蛋白抗體
別    名 C1orf29; GS3686; IF44L_HUMAN; IFI44L; Interferon-induced protein 44-like.  
Specific References  (1)     |     bs-15551R has been referenced in 1 publications.
[IF=5.923] Cheng Chen. et al. Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy. Int J Mol Sci. 2021 Jan;22(23):13116  ELISA,IHC ;  Rat.  
研究領域 細胞生物  微生物學  細胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 51 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFI44L: 101-200/452 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 IFI-44L is a 452 amino acid cytoplasmic protein that shares some sequence similarities with IFI-44. IFI-44 is a cytoplasmic protein that aggregates to form microtubule structures. The genes that encode IFI-44L and IFI-44 are located on chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
Exhibits a low antiviral activity against hepatitis C virus.

Subcellular Location:
Cytoplasm (Potential).

Similarity:
Belongs to the IFI44 family.

SWISS:
Q53G44

Gene ID:
10964

Database links:

Entrez Gene: 10964 Human

Omim: 613975 Human

SwissProt: Q53G44 Human

Unigene: 731680 Human



產品圖片
Sample: Du145 Cell (Human) Lysate at 30 ug Primary: Anti-IFI44L (bs-15551R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51kD Observed band size: 51kD
Sample:MCF-7 Cell (Human) Lysate at 30 ug Primary: Anti-IFI44L (bs-15551R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51kD Observed band size: 51kD
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