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FER1L6 Rabbit pAb (bs-16073R)  
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50ul/1180.00元
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大包裝/詢價
產品編號 bs-16073R
英文名稱 FER1L6 Rabbit pAb
中文名稱 FER1L6蛋白抗體
別    名 C8orfK23; Fer-1-like protein 6; FER1L6; FR1L6_HUMAN.  
研究領域 細胞生物  免疫學  發育生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Rabbit,Pig,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 209 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FER1L6: 1751-1857/1857 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 FER1L6 (fer-1-like protein 6) is a 1,857 amino acid single-pass membrane protein that belongs to the ferlin family and contains six C2 domains. The gene encoding FER1L6 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Subcellular Location:
Membrane.

Similarity:
Belongs to the ferlin family.
Contains 6 C2 domains.

SWISS:
Q2WGJ9

Gene ID:
654463

Database links:

Entrez Gene: 654463 Human

SwissProt: Q2WGJ9 Human

Unigene: 632058 Human



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