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FLJ36180 Rabbit pAb (bs-16126R)  
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產品編號 bs-16126R
英文名稱 FLJ36180 Rabbit pAb
中文名稱 RNF209/環指蛋白209抗體
別    名 EC 6.3.2.-; FLJ36180; MGC138638; MGC138639; Probable E3 ubiquitin-protein ligase TRIML1; RING finger protein 209; RNF209; TRIML_HUMAN; Triml1; Tripartite motif family like protein 1; Tripartite motif family-like protein 1.  
研究領域 細胞生物  免疫學  轉錄調節因子  表觀遺傳學  環指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLJ36180: /351-450/468 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation.TRIML1 (tripartite motif family-like 1), also known as RNF209 (RING finger protein 209), is a 468 amino acid protein that contains one SPRY domain and one RING-type zinc finger. Due to the presence of a RING-type zinc finger motif, TRIML1 may be involved in protein degradation events within the cell.

Function:
Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development.

Subunit:
Interacts with USP5 (By similarity).

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

SWISS:
Q8N9V2

Gene ID:
339976

Database links:

Entrez Gene: 339976 Human

Entrez Gene: 244448 Mouse

SwissProt: Q8N9V2 Human

SwissProt: Q8BVP1 Mouse

Unigene: 348618 Human

Unigene: 64542 Mouse



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with FLJ36180 polyclonal antibody, unconjugated (bs-16126R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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