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SCD5 Rabbit pAb (bs-17278R)  
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50ul/1180.00元
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產品編號 bs-17278R
英文名稱 SCD5 Rabbit pAb
中文名稱 硬脂酰輔酶A去飽和酶5抗體
別    名 ACOD4; Acyl CoA desaturase 4; Acyl-CoA-desaturase 4; FADS4; FLJ21032; HSCD5; SCD2; SCD4; SCD5; SCD5_HUMAN; Stearoyl CoA 9 desaturase; stearoyl CoA desaturase 4; Stearoyl CoA desaturase 5; Stearoyl-CoA 9-desaturase; Stearoyl-CoA desaturase 5.  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCD5: 251-330/330 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]

Function:
Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Detected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung.

Similarity:
Belongs to the fatty acid desaturase family.

SWISS:
Q86SK9

Gene ID:
79966

Database links:

Entrez Gene: 79966 Human

Omim: 608370 Human

SwissProt: Q86SK9 Human

Unigene: 379191 Human



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