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SPATA18 Rabbit pAb (bs-17642R)  
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產品編號 bs-17642R
英文名稱 SPATA18 Rabbit pAb
中文名稱 精子發生相關蛋白18抗體
別    名 1700067I02Rik; FLJ32906; MGC93900; Mieap; mitochondria eating protein; SPATA18; Spermatogenesis associated 18; spermatogenesis associated 18 homolog(rat); Spermatogenesis associated protein 18; Spermatogenesis-associated protein 18; SPETEX1; SPT18_HUMAN.  
研究領域 細胞生物  發育生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse,Chimpanzee, Macaque Monkey,Gorilla, Orangutan)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 63 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPATA18: 401-500/538 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SPATA18 is a 538 amino acid protein that is thought to play a role in cell differentiation during spermatogenesis, particularly during development from late elongate spematids to mature spermatozoa. Localizing to cytoplasm, SPATA18 is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Function:
Potential role in spermatogenesis, especially in cell differentiation from late elongate spematids to mature spermatozoa.

Subunit:
Interacts (via coiled-coil domains) with BNIP3L (via BH3 domain). Interacts (via coiled-coil domains) with BNIP3 (via BH3 domain).

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the MIEAP family.

SWISS:
Q8TC71

Gene ID:
132671

Database links:

Entrez Gene: 132671 Human

Entrez Gene: 289586 Rat

Omim: 612814 Human

SwissProt: Q8TC71 Human

SwissProt: Q6AYL6 Rat

Unigene: 527090 Human



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