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IFNB1 Rabbit pAb (bs-23733R)  
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產(chǎn)品編號(hào) bs-23733R
英文名稱 IFNB1 Rabbit pAb
中文名稱 干擾素β抗體
別    名 Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN; IFNB_MOUSE.  
Specific References  (3)     |     bs-23733R has been referenced in 3 publications.
[IF=6.107] Nan Zang. et al. cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease. ISCIENCE. 2022 Sep;:105145  WB ;  Mouse.  
[IF=5.191] Huiqing Hu. et al. cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress. Faseb J. 2022 May;36(5):e22266  WB ;  Mouse.  
[IF=3.871] H.Q. Hu. et al. The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes. Mol Cell Endocrinol. 2020 Dec;518:110890  WB ;  Mouse.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  干擾素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Rat (predicted: Mouse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse IFNB1: 22-100/184 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.

Function:
Has antiviral, antibacterial and anticancer activities.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Similarity:
Belongs to the alpha/beta interferon family.

Database links:

Entrez Gene: 15977 Mouse

SwissProt: P01575 Mouse



產(chǎn)品圖片
Sample: Lung (Rat) Lysate at 40 ug Primary: Anti-IFN-Beta (bs-23733R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20 kD Observed band size: 32 kD
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