| 產(chǎn)品編號 | bsm-30094M |
| 英文名稱 | human CD8 Mouse mAb |
| 中文名稱 | 小鼠抗人CD8單克隆抗體 |
| 別 名 | CD8 antigen, alpha polypeptide(p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen. |
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Specific References (2) | bsm-30094M has been referenced in 2 publications.
[IF=9.918] Daijun Zhou. et al. An injectable miR181a-IFI6 nanoparticles promote high-quality healing of radiation-induced skin injury. MATER TODAY ADV. 2022 Aug;15:100267 FC ; Human.
[IF=9.776] Yingli Wang. et al. Paclitaxel derivative-based liposomal nanoplatform for potentiated chemo-immunotherapy. J Control Release. 2022 Jan;341:812 IF ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞表面分子 t-淋巴細(xì)胞 |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號 | HIT8a |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1ug/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 27 kDa |
| 檢測分子量 | 32-34 |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human CD8 |
| 亞 型 | Mouse IgG1, k |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. Similarity: Belongs to the PMP-22/EMP/MP20 family. SWISS: P01732 Gene ID: 925 Database links: Entrez Gene: 925 Human Entrez Gene: 926 Human Entrez Gene: 12525 Mouse Entrez Gene: 12526 Mouse Omim: 186910 Human SwissProt: P01732 Human SwissProt: P10966 Human SwissProt: P01731 Mouse SwissProt: P10300 Mouse Unigene: 405667 Human Unigene: 85258 Human Unigene: 1858 Mouse Unigene: 333148 Mouse |
| 產(chǎn)品圖片 |
scatter diagram showing peripheral blood lymphocytes stained with CD8. The cells were incubated with the antibody (bsm-30094M) for 30 min at 22°C.The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
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