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Human IL-13 ELISA Kit (bsk11003)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
96T/2900.00元
大包裝/詢價
產品編號 bsk11003
英文名稱 Human IL-13 ELISA Kit
中文名稱 人白細胞介素13酶聯免疫試劑盒
別    名 IL13; IL-13; P600; interleukin 13  
克 隆 號
種    屬 Human
線性范圍 93.75 - 6000 pg/mL
應用范圍 S/P/CC
檢測限 47 pg/mL
適用樣品基質 cell culture supernates, serum, and plasma.
保存條件 Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.).
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Interleukin-13 (IL-13) is a 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by Th1, Th2, Th17, NK, and mast cells, visceral smooth muscle cells, eosinophils, and basophils. This pattern is similar to the expression of Interleukin-4 (IL-4) but also includes subsets of Th1 and Th17 cells that do not secrete IL-4. IL-13 circulates as a monomer and has two internal disulfide bonds that contribute to its bundled four α-helix configuration. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. Despite the low homology, it exhibits cross-species activity between human, mouse, and rat. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. On B cells, it promotes cellular activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fcε RII. Polymorphisms and upregulation of IL-13 are associated with atopy, asthma, airway hyperresponsiveness, and tissue fibrosis.

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