| 產品編號 |
bsk11060 |
| 英文名稱 |
Human IL-24/MDA-7 ELISA Kit
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| 中文名稱 |
人白細胞介素24酶聯免疫試劑盒 |
| 別 名 |
IL24_HUMAN; Interleukin-24; IL-24; Melanoma differentiation-associated gene 7 protein; MDA-7; Suppression of tumorigenicity 16 protein. |
| 克 隆 號 |
|
| 種 屬 |
Human |
| 線性范圍 |
62.50 - 4,000 pg/mL |
| 應用范圍 |
S/P/CC |
| 檢測限 |
31 pg/mL |
| 適用樣品基質 |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| 保存條件 |
Store at 4°C & -20°C for 12 months. |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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