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TNMD Rabbit pAb (bs-41215R)  
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產品編號 bs-41215R
英文名稱 TNMD Rabbit pAb
中文名稱 腱調蛋白/軟骨調節素樣1蛋白抗體
別    名 BRICD4; BRICHOS domain containing 4; CHM1 LIKE; CHM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TEM; Tendin; Tenomodulin; Tenomodulin protein; TNMD; TNMD_HUMAN; UNQ771/PRO1565.  
研究領域 心血管  血管內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000,IHC-P=1:400-800,IHC-F=1:400-800,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human TNMD protein 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].

Function:
May be an angiogenesis inhibitor.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the chondromodulin-1 family.
Contains 1 BRICHOS domain.

SWISS:
Q9H2S6

Gene ID:
64102

Database links:

Entrez Gene: 64102 Human

Entrez Gene: 64103 Mouse

Entrez Gene: 64104 Rat

Omim: 300459 Human

SwissProt: Q9H2S6 Human

SwissProt: Q9EP64 Mouse

SwissProt: Q9ESC2 Rat

Unigene: 132957 Human

Unigene: 46221 Mouse

Unigene: 26691 Rat



產品圖片
Sample: Lane 1: Skeletal muscle (Rat) Lysate at 40 ug Lane 2: Skeletal muscle (Mouse) Lysate at 40 ug Primary: Anti-TNMD (bs-41215R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 37 kD
Sample: Lane 1: Muscle (Rat) Lysate at 40 ug Lane 2: HepG2 (Human) Cell Lysate at 30 ug Lane 3: Heart (Rat) Lysate at 40 ug Lane 4: SW480 (Human) Cell Lysate at 30 ug Primary: Anti- TNMD (bs-41215R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 35 kD
Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TNMD) Polyclonal Antibody, Unconjugated (bs-41215R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TNMD) Polyclonal Antibody, Unconjugated (bs-41215R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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