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Creatine Kinase MB (CK-MB) Mouse mAb (V1001)  
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產品編號 V1001
英文名稱 Creatine Kinase MB (CK-MB) Mouse mAb
中文名稱 肌酸激酶同工酶MB單克隆抗體
克 隆 號 6B12
理論分子量 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 ≥0.6 mg/ml
緩 沖 液 potassium phosphate buffer and sodium chloride. No preservatives are added.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

Function:
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.

Subcellular Location:
Cytoplasmic and Mitochondrial

Similarity:
Belongs to the ATP:guanido phosphotransferase family.
Contains 1 phosphagen kinase C-terminal domain.
Contains 1 phosphagen kinase N-terminal domain.

SWISS:
P12277

Gene ID:
1158

Database links:

Entrez Gene: 1152 Human

Entrez Gene: 1158 Human

Omim: 123310 Human

SwissProt: P06732 Human

SwissProt: P12277 Human 



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