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human CD274 (B7-H1, PD-L1) Mouse mAb (bsm-30139M)  
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100ug/1880.00元
200ug(PBS only)/5600.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bsm-30139M
英文名稱 human CD274 (B7-H1, PD-L1) Mouse mAb
中文名稱 人CD274 (B7-H1, PD-L1)單克隆抗體
別    名 Programmed cell death 1 ligand 1; CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed death ligand 1; RGD1566211.  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號(hào) 4C11
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測(cè)分子量 40
性    狀 Liquid
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M PBS (pH7.4).
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 TThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

產(chǎn)品圖片
Blank control(black line):MDA-MB-231. Primary Antibody (green line): Mouse Anti-Human PD-L1 antibody (bsm-30139M) Dilution:1ug/Test; Secondary Antibody(white blue line): Goat anti-mouse IgG-FITC Dilution: 0.5ug/Test. Isotype control(orange line): Normal Mouse IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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