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Anti-B7-H4 & CD3 Reference Antibody (Gen1047 Biosimilar) (BIO0995SM)  
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100ug/詢價
1mg/詢價
5mg/詢價
大包裝/詢價

產品編號 BIO0995SM
英文名稱 Anti-B7-H4 & CD3 Reference Antibody (Gen1047 Biosimilar)
別    名 B7-H4 / VTCN1 & CD3; Gen1047  
抗體來源
克隆類型 Monoclonal
交叉反應 Human
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 144.48kDa
性    狀 Lyophilized
亞    型 IgG-like
純化方法 Protein A
緩 沖 液 100 mM Pro-Ac 20mM Arg pH 5.0
保存條件 -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹
產品圖片
Co-incubation of Gen1047 with Jurkat cells, then with the addition of huB7H4 CHO-k cells for 6 hours. Bright-Lite was used to detect the fluorescent signal. As shown in fig, Gen1047 was able to activate the NF-AT signaling pathway.
Gen1047 bound to huCD3e-jurkat cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Gen1047 bound to huCD3e-jurkat cells, and the EC50 was 132.600 nM.
Gen1047 bound to huB7-H4 CHO-K cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Gen1047 bound to huB7-H4 CHO-K cells, and the EC50 was 6.894 nM.
Gen1047 bound to B7-H4 protein, and then rebounded to secondary antibodies (Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Gen1047 bound human B7-H4 Protein-His, and the EC50 was 0.07805 nM.
The purity of Anti-B7-H4 & CD3 Reference Antibody (Gen1047) is 97.20%, determined by SEC-HPLC.
Anti-B7-H4 & CD3 Reference Antibody (Gen1047) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The detected molecular weight of Anti-CD3 & B7-H4 Reference Antibody (Gen1047) is 144.74 kDa
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