麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲高清一二三区,91成年视频,爆乳放荡的女教师bd
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-VEGF/PE-Cy3 Conjugated antibody (bs-1313R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1313R-PE-Cy3
英文名稱 Rabbit Anti-VEGF/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的血管內皮生長因子抗體
別    名 Vascuoar endothelial growth factor A; VEGF A; vascular endothelial growth factor A isoform 2 precursor; Vegf; VEGFA; MGC70609; MVCD1; VEGF; VPF; VEGFA_HUMAN; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGF A Precursor.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  信號轉導  生長因子和激素  血管內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Rabbit,  (predicted: Chicken, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VEGF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

Function:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Subunit:
Homodimer; disulfide-linked. Also found as heterodimer with PGF.

Subcellular Location:
Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.

Tissue Specificity:
Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed.

DISEASE:
Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1) [MIM:603933]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.

Similarity:
Belongs to the PDGF/VEGF growth factor family.

Database links:

Entrez Gene: 403802 Dog

Entrez Gene: 7422 Human

Entrez Gene: 22339 Mouse

Entrez Gene: 83785 Rat

Omim: 192240 Human

SwissProt: Q9MYV3 Dog

SwissProt: P15692 Human

SwissProt: Q00731 Mouse

SwissProt: P16612 Rat

Unigene: 73793 Human

Unigene: 282184 Mouse

Unigene: 1923 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

血管內皮細胞生長因子(VEGF)是一種特異作用于血管內皮細胞的多功能細胞因子,它能引起血管通透性增加,引起細胞外基質成分改變,誘導血管形成.在炎癥、創傷愈合、心臟缺血、動脈粥樣硬化、糖尿病性視網膜病變及腫瘤形成等與血管生成和病變有關的諸多病理過程中起重要作用.
VEGF與血管生成有關,因而與腫瘤生長有很大關系,近年來受到很多關注。
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产一区二区视频精品 | 亚洲AV无码一区二区三区性色 | 超碰最新网址 | 九九九九热精品免费视频点播观看 | 欧美日韩一二区 | 欧美精品成人一区二区三区四区 | 免费福利视频一区二区三区 | 色欲AV久久一区二区三区 | 亚洲二区三区视频 | 欧美一级大胆视频 | 亚洲毛片无码专区亚洲乱 | 亚洲日韩成人无码 | 九一精品国产白色高跟鞋 | 国产XXXXXX农村野外 | 国产成人无码A片免费男男中文 | 欧美性猛交xxxx乱大交久久 | 91精品视频在线看 | 亚洲成AV人片香蕉片 | 亚洲视频天天射 | 羞羞答答av成人免费看 | 国产成年人黄色视频 | 成人一区二区在线 | 亚洲地区一二三色 | 天天夜碰日日摸日日澡性色av | 日本在线二区 | 丰满少妇被猛烈进入毛片 | 18禁无遮挡无码网站免费 | 亚洲精品乱码久久久久久中文字幕 | 亚洲精品久久久久中文字幕二区 | 精品区在线 | 一级特毛片 | 亚洲在线中字幕 | 国产主播AV福利精品一区 | 国产日韩欧美精品在线观看 | 扒开粉嫩的小缝喷白浆h | 亚洲精品无码MV在线观看软件 | 真实国产乱子伦对白视频不卡 | 日韩在线免费视频观看 | 久久久久久久久久久久久国产精品 | 久久激情视频 | 午夜免费视频网站 |