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Rabbit Anti-SCUBE1/BF488 Conjugated antibody (bs-9903R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9903R-BF488
英文名稱 Rabbit Anti-SCUBE1/BF488 Conjugated antibody
中文名稱 BF488標記的新型血小板相關血管內皮分泌蛋白SCUBE1抗體
別    名 SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCUBE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.

Function:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.

Subunit:
Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3.

Subcellular Location:
Secreted. Cell membrane.

Tissue Specificity:
Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.

Post-translational modifications:
N-glycosylated.
Could be proteolytically cleaved to release a smaller active fragment.

Similarity:
Contains 1 CUB domain.
Contains 9 EGF-like domains.

Database links:

Entrez Gene: 80274 Human

Entrez Gene: 64706 Mouse

Entrez Gene: 100524621 Pig

Entrez Gene: 315174 Rat

Omim: 611746 Human

SwissProt: Q8IWY4 Human

SwissProt: Q6NZL8 Mouse

Unigene: 133995 Human

Unigene: 40393 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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