麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日本久久综合,日本免费在线看,亚洲第一男人天堂
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TNFSF14/APC Conjugated antibody (bs-2462R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2462R-APC
英文名稱 Rabbit Anti-TNFSF14/APC Conjugated antibody
中文名稱 APC標記的腫瘤壞死因子配體超家族成員14抗體
別    名 CD 258; CD258; CD258 antigen; Delta transmembrane LIGHT; Herpes virus entry mediator ligand; Herpesvirus entry mediator A; Herpesvirus entry mediator ligand; herpesvirus entry mediator-ligand; HVEM L; HVEM-L; HVEML; Ligand for herpesvirus entry mediator; LIGHT; LTg; soluble form; TNF14; TNF14_HUMAN; TNFSF 14; TNFSF14; TNFSF14 protein; TR 2; TR2; Tumor necrosis factor (ligand) superfamily, member 14; Tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily, member 14; Tumor necrosis factor receptor like 2; tumor necrosis factor receptor-like 2; Tumor necrosis factor superfamily member 14; Tumor necrosis factor superfamily member LIGHT.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  t-淋巴細胞  細胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
LIGHT protein is a type II transmembrane protein and a tumor necrosis factor (TNF) ligand superfamily member (TNFSF14). LIGHT is expressed on activated T cells and immature dendritic cells and its receptors have been identified as lymphotoxin-Beta receptor (LTBetaR) and the herpesvirus entry mediator (HVEM), both of which lack the cytoplasmic sequence termed as "death domain." LIGHT is first identified as HVEM ligand (HVEM-L) and a deterrent to herpesvirus infection according to its ability to compete with HSV glycoprotein D for HVEM binding. As a T cell-derived costimulatory ligand, TNFSF14 plays a crucial role in T cell activation and proliferation by LIGHT-LTBetaR interaction, and it is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells. Additionally, recent studies also establish a direct role for LIGHT in NK activation/expansion via LIGHT-HVEM interaction, and thus breaking T-cell tolerance at the tumor site. Accordingly, LIGHT is suggested to be involved in CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Although known as lymphotoxin-Gamma, LIGHT plays a minimal role in lymphoid tissue development in contrast with LT-Alpha and Beta. This protein was also demonstrated to inhibit TNF-Alpha-mediated but not Fas- or TRAIL-mediated apoptosis of human primary hepatocytes.

Function:
Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

Subunit:
Homotrimer.

Subcellular Location:
Tumor necrosis factor ligand superfamily member 14, membrane form: Cell membrane; Single-pass type II membrane protein.
Tumor necrosis factor ligand superfamily member 14, soluble form: Secreted.
Isoform 2: Cytoplasm.

Tissue Specificity:
Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.

Post-translational modifications:
N-glycosylated.
The soluble form of isoform 1 derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 8740 Human

Omim: 604520 Human

SwissProt: O43557 Human

Unigene: 129708 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 狠狠躁18三区二区一区 | 国产一区二区美女视频 | 少妇又紧又深又湿又爽视频 | 无码精品人妻一区二区三区九里奈 | 一二三区不卡 | 中国少妇bbbbxxxx | 国产精品久久久久久麻豆一区胖胖 | 1000部夫妻午夜免费 | 裸体久久女人亚洲精品 | 性一交一乱一色一视频麻豆 | 国产jizz18高清视频 | 国产乱妇乱子在线播放视频 | 在线播放亚洲第一字幕 | 精品国产肉丝袜久久 | 国产精品人妻一区二区三区a | 国产精品一区二区三区三州 | wwwxxxxx日本 | 国产00粉嫩馒头一线天萌白酱 | 无码精品A片一区二区 | 短剧教父1至87集免费观看 | 小蝌蚪草莓向日葵 | 亚洲第一成年人视频 | 中文字幕一区二区三区波多野结衣 | 国产精品萝li | 天天摸天天操天天干 | 国产一区二区三区在线免费观看 | 免费看日批视频 | 久久精品永久免费 | 成人亚洲A片V一区二区三区色欲 | 亚洲AV无码一区二区三区鸳鸯影院 | 顶级毛片 | 精品1区2区3区4区产品乱码9 | 日韩中文字幕免费 | 高清国产视频在线 | 日韩在线黄色片 | 日本免费网站看大片视频 | 欧美激情一区二区三级高清视频 | 99久久精品这里只有精品 | 99久久久国产精品免费调教网站 | 伊伊综合在线视频无码 | 99久久夜色精品国产亚洲 |