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Rabbit Anti-SLAMF6/LY108/BF555 Conjugated antibody (bs-2682R-BF555)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2682R-BF555
英文名稱 Rabbit Anti-SLAMF6/LY108/BF555 Conjugated antibody
中文名稱 BF555標記的SLAMF6抗體
別    名 LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  細胞表面分子  細胞類型標志物  自然殺傷細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SLAMF6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.

Function:
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.

Subunit:
Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.

Database links:

Entrez Gene: 114836 Human

Entrez Gene: 30925 Mouse

Omim: 606446 Human

SwissProt: Q96DU3 Human

SwissProt: Q9ET39 Mouse

Unigene: 492348 Human

Unigene: 486404 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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