麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
大地资源在线观看免费高清官网,唐人街探案1免费播放,www在线看片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GRK1/PE-Cy5 Conjugated antibody (bs-1082R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1082R-PE-Cy5
英文名稱 Rabbit Anti-GRK1/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的G蛋白偶合受體激酶1抗體
別    名 G-protein coupled receptor kinase 1; GRK1; GPRK1; RK; Grk1; Rhok; RHODOPSIN KINASE; RK_HUMAN.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  神經生物學  信號轉導  激酶和磷酸酶  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Chicken, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GRK1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq]

Function:
Phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Subcellular Location:
Membrane.

Tissue Specificity:
Retina and pineal gland.

Post-translational modifications:
Autophosphorylated.
Farnesylation is required for full activity.

DISEASE:
Defects in GRK1 are a cause of congenital stationary night blindness Oguchi type 2 (CSNBO2) [MIM:613411]. It is non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. Congenital stationary night blindness Oguchi type is associated with fundus discoloration and abnormally slow dark adaptation.

Similarity:
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
GPRK subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
Contains 1 RGS domain.

Database links:

Entrez Gene: 6011 Human

Entrez Gene: 24013 Mouse

Omim: 180381 Human

SwissProt: Q15835 Human

SwissProt: Q9WVL4 Mouse

Unigene: 103501 Human

Unigene: 721727 Human

Unigene: 257501 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

G蛋白偶聯受體激酶1(GRK1)是催化激動劑誘導的GPCR磷酸化以及啟動GPCR脫敏的關鍵激酶,主要用于GRK細胞膜轉位和對GRK功能的影響.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲一二区在线观看 | 国产高清吃奶成免费视频网站 | 一区二区黄色 | 亚洲欧美在线视频 | 免费a国产| 91网站免费观看 | 亚洲v国产v天堂a无码二区久久 | 无码午夜成人1000部免费视频 | 成人网站在线进入爽爽爽 | 18禁免费无码无遮挡网站 | 欧美成一区| 天天干天天射综合网 | 永久视频在线观看 | 国产又粗又大又硬点视频 | 人妻精品久久无码专区精东影业 | 少妇的丰满人妻HD高清 | 成年视频在线播放 | 激情亚洲AV无码日韩色 | 不用播放器的av网站 | 无码人妻一区二区三区免费手机 | 日本高清www | 久久精品在线观看视频 | 国产综合精品五月丁香好久久 | 亚洲一区二区不卡视频 | 91产国在线观看动作片喷水 | 国产精品s房调教打屁股 | 国产精品久久久久久精 | 一区二区三区四区毛片 | 男人av网 | 日韩免费无码人妻波多野 | WWW夜片内射视频在观看视频 | 大陆黄色一级片 | 成人在线视频一区二区三区 | 在线免费精品视频 | 欧美V亚洲V日韩V最新在线 | av在线播放色| 国产欧美成人一区二区a片 一人之下在线免费观看 | 国产高清www午色夜 日日干天天操 | 在线观看国产小视频 | 精品国产欧美日韩在线不卡 | www97影院 |