| 產品編號 | bs-4727R-FITC |
| 英文名稱 | Rabbit Anti-Macrophage mannose receptor 1/FITC Conjugated antibody |
| 中文名稱 | FITC標記的巨噬細胞甘露糖受體抗體 |
| 別 名 | Mannose Receptor; Macrophage mannose receptor 1; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor 1; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; OTTHUMP00000045206; MRC1_HUMAN; MRC1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1. |
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Journal
PMID
IF
Application
[IF=5.411] Jiyuan Piao. et al. Substance P blocks β-aminopropionitrile-induced aortic injury through modulation of M2 monocyte-skewed monocytopoiesis. Transl Res. 2021 Feb;228:76 IHC ; Rat.
[IF=5.23] Blomgran, Parmis, et al. "A possible link between loading, inflammation and healing: Immune cell populations during tendon healing in the rat." Scientific Reports 6 (2016): 29824. FCM ; Rat.
[IF=4.996] Kagioka Takumi. et al. Lithium carbonate accelerates the healing of apical periodontitis. SCI REP-UK. 2023 May;13(1):1-12 IF ; Rat.
[IF=4.15] Zhu, Dan, et al. "M2 Macrophage Transplantation Ameliorates Cognitive Dysfunction in Amyloid-β-Treated Rats Through Regulation of Microglial Polarization." Journal of Alzheimers Disease: 1-13. Rat.
[IF=3.149] Jing Wang. et al. Mesenchymal stem cells regulate M1 polarization of peritoneal macrophages through the CARD9-NF-κB signaling pathway in severe acute pancreatitis. J HEPATO-BIL-PAN SCI. 2022 Jun 23 FC ; Mouse.
[IF=3.078] Simon Harper. et al. Portal venous repopulation of decellularised rat liver scaffolds with syngeneic bone marrow stem cells. J Tissue Eng Regen M. 2020 Oct;14(10):1502-1512 FC ; Rat.
[IF=2.895] Shao N et al. A Multi‐Functional Silicon Nanoparticle Designed for Enhanced Osteoblast Calcification and Related Combination Therapy. Macromol Biosci. 2019 Nov 10:e1900255. FCM ; Mouse.
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| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領域 | 細胞生物 免疫學 轉錄調節因子 細胞膜受體 糖蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, ) |
| 產品應用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 160kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRC1/CD206 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq]. Function: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. Subcellular Location: Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Similarity: Contains 8 C-type lectin domains. Contains 1 fibronectin type-II domain. [SIMILARITY] Contains 1 ricin B-type lectin domain. Database links: Entrez Gene: 4360 Human Entrez Gene: 17533 Mouse Omim: 153618 Human SwissProt: P22897 Human SwissProt: Q61830 Mouse Unigene: 75182 Human Unigene: 2019 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 巨噬細胞甘露糖受體,主要存在于巨噬細胞膜表面的模式識別受體，能夠特異性識別甘露糖、巖藻糖或N-乙酰葡糖胺，介導巨噬細胞吞噬抗原，啟動免疫反應. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
