麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最新一区二区三区,真人一级毛片视频,草草视频免费
Rabbit Anti-Angiopoietin-1/Gold Conjugated antibody (bs-0800R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0800R-Gold
英文名稱 Rabbit Anti-Angiopoietin-1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的血管生成素-1抗體
別    名 ANG; AGP 1; AGP1; AGPT; ANG 1; ANG1; Angiopoietin1; Angiogenin; ANGPT 1; ANGPT1; ANGPT-1; Angiopoietin-1; Angiopoietin 1; ANG-1; angiopoietin-1 isoform 1 precursor; ANGP1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Angiopoietin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].

Function:
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In quiescent vessels, ANGPT1 oligomers recruit TEK to cell-cell contacts, forming complexes with TEK molecules from adjoining cells, and this leads to preferential activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascades. In migrating endothelial cells that lack cell-cell adhesions, ANGT1 recruits TEK to contacts with the extracellular matrix, leading to the formation of focal adhesion complexes, activation of PTK2/FAK and of the downstream kinases MAPK1/ERK2 and MAPK3/ERK1, and ultimately to the stimulation of sprouting angiogenesis. Mediates blood vessel maturation/stability. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Subunit:
Homooligomer. Interacts with TEK/TIE2.

Subcellular Location:
Secreted.

Post-translational modifications:
Glycosylated.

Similarity:
Contains 1 fibrinogen C-terminal domain.

Database links:

Entrez Gene: 284 Human

Entrez Gene: 11600 Mouse

Omim: 601667 Human

SwissProt: Q15389 Human

SwissProt: O08538 Mouse

Unigene: 369675 Human

Unigene: 309336 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Ang1/2與血管生成關(guān)系最為密切,目前有關(guān)該家族成員在腫瘤血管生成中的研究正日益增多。近年來也用于糖尿病導(dǎo)致的血管損傷研究也是熱門課題。
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产尤物av尤物在线观看 | 9l国产精品久久久久麻豆 | 久久精品国语对话 | 国产精品美脚玉足脚交欧美 | 中文字幕一区二区三区视频 | 中文字幕亚洲第一页 | 91激情视频在线播放 | 精品视频一区二区 | 欧美人妖另类hd1080p | 亚洲精品乱码久久久久久久久久 | 8888四色奇米在线观看 | 久久人人九九 | 久久夜色精品国产噜噜亚洲AV | 啊啊啊免费网站 | 69国产在线观看 | 国产亚洲综合性久久久影院 | 麻豆在网站1区 | 亚洲综合久久av一区二区三区 | 99人精品福利在线观看 | 好男人蜜桃av久久久久久蜜桃 | 中文字幕狠狠 | 国语少妇高潮对白在线 | 日女av在线 | 国产精品乱子伦XXXX | 伊人成人综同网wwwyiren22co | 无码精品久久久久久人妻中字 | 日日噜噜噜夜夜爽爽狠狠 | 国产另类ts人妖高潮 | 五月婷婷俺也去 | 被公牛日到了高潮 | 亚洲精品a级九色 | 中文久久久久 | 日韩欧美成人一区二区 | 无码免费视频AAAAAA片草莓 | 99热精品在线 | 丝袜无码一区二区三区 | 自拍视频啪| 午夜精品久久久久久中宇69 | 久久精品无码一区二区三区不卡 | 国产综合社区在线视频 | av午夜久久蜜桃传媒软件 |