| 產(chǎn)品編號(hào) | bs-9340R-Gold |
| 英文名稱 | Rabbit Anti-MARCH6/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的膜相關(guān)環(huán)指蛋白6抗體 |
| 別 名 | Doa10 homolog; E3 ubiquitin protein ligase MARCH6; MARCH 6; MARCH VI; MARCHVI; Membrane associated RING CH protein VI; Membrane associated ring finger (C3HC4) 6; Membrane associated RING finger protein 6; Protein TEB 4; Protein TEB4; RNF 176; RNF176; TEB 4; TEB4; RING finger protein 176; MARH6_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞周期蛋白 通道蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 103kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MARCH6 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes. Function: E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1. Subunit: Interacts with DIO2. Subcellular Location: Endoplasmic reticulum membrane; Multi pass membrane protein. Tissue Specificity: Present in brain (at protein level). Post-translational modifications: Auto-ubiquitinated, which results in proteasomal degradation. Similarity: Contains 1 RING-CH-type zinc finger. Database links: Entrez Gene: 10299 Human Entrez Gene: 223455 Mouse Omim: 613297 Human SwissProt: O60337 Human SwissProt: Q6ZQ89 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
