麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
国产区二,亚洲日韩欧美内射教官,WWW国产亚洲精品久久
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-LRP1(Ser4523)/RBITC Conjugated antibody (bs-5409R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5409R-RBITC
英文名稱 Rabbit Anti-phospho-LRP1(Ser4523)/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的磷酸化低密度脂蛋白受體相關蛋白1抗體
別    名 A2MR; Alpha 2 macroglobulin receptor; alpha 2MR; APOER; Apolipoprotein E receptor; APR; CD 91; CD91; CD91 antigen; Low density lipoprotein receptor related protein 1; Low density lipoprotein related protein 1; LRP 1; LRP 515; LRP 85; LRP; LRP ICD; LRP1; LRP1 protein; LRP515.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 心血管  免疫學  神經生物學  信號轉導  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 500kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

Subunit:
Heterodimer of an 85-kDa membrane-bound carboxyl subunit and a non-covalently attached 515-kDa N-terminal subunit. Intracellular domain interacts with MAFB (By similarity). Found in a complex with PID1/PCLI1, LRP1 and CUBNI. Interacts with SNX17, PID1/PCLI1, PDGF and CUBN. The intracellular domain interacts with SHC1, GULP1 and DAB1. Interacts with LRPAP1. Interacts with bacterial exotoxins.

Subcellular Location:
Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm. Nucleus. Note=After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus.

Tissue Specificity:
Most abundant in liver, brain and lung.

Similarity:
Belongs to the LDLR family.
Contains 22 EGF-like domains.
Contains 31 LDL-receptor class A domains.
Contains 34 LDL-receptor class B repeats.

Database links:

Entrez Gene: 4041 Human

Entrez Gene: 16973 Mouse

Entrez Gene: 293649 Rat

Omim: 603506 Human

SwissProt: O75197 Human

SwissProt: Q91VN0 Mouse

Unigene: 6347 Human

Unigene: 274581 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品亚洲专一区二区三区 | 亚洲最大成人免费网站 | caopo在线 | 美女中文字幕视频 | 国内不卡的一区二区三区中文字幕 | 久久精品亚洲女星A级视频 邻居少妇张开双腿让我爽一夜 | 亚洲精品综合欧美一区二区三区 | 免费无码肉片在线观看 | 沦为公交两奶头春药高潮迭起 | 色网小说| 国产欧美精品一区二区三区 | 久久久久日本精品毛片蜜桃成熟时 | 水野优香在线亚洲一区 | 56精品视频在线播放免费观看 | 久久国产精品一区二区三区四区 | 三级视频在线观看 | 欧美巨大黑人xxxxⅹ视频动漫 | 欧美综合天天夜夜久久 | www.九色 | 久色视频 | 狠狠热精品免费视频 | 日本无删减在线 | 免费毛片全部不收费的 | 国内精品久久久久久久小说 | 国产视频中文字幕 | 日本成人中文字幕 | xxxxxxxxx欧美 | 国产人妻人伦精品潘金莲 | 美女一级黄色大片 | 久久激情视频 | 九九九全国免费 | 国产高清视频免费观看 | 99久久免费国产精品热 | 日本XXX免费高清色视频在线观看 | 国产精品区在线 | 亚洲精品乱码久久久久久 | 青青青国产在线视频在线观看 | 操操操操操操操 | www.com草莓视频 | 国产视频一区二区三区在线 | 欧美日韩国产精品成人 |