麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
youjazz性欧美,欧美片网站免费,日韩国产一区二区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-LRP1(Ser4523)/BF647 Conjugated antibody (bs-5409R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5409R-BF647
英文名稱 Rabbit Anti-phospho-LRP1(Ser4523)/BF647 Conjugated antibody
中文名稱 BF647標記的磷酸化低密度脂蛋白受體相關蛋白1抗體
別    名 A2MR; Alpha 2 macroglobulin receptor; alpha 2MR; APOER; Apolipoprotein E receptor; APR; CD 91; CD91; CD91 antigen; Low density lipoprotein receptor related protein 1; Low density lipoprotein related protein 1; LRP 1; LRP 515; LRP 85; LRP; LRP ICD; LRP1; LRP1 protein; LRP515.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 心血管  免疫學  神經生物學  信號轉導  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 500kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

Subunit:
Heterodimer of an 85-kDa membrane-bound carboxyl subunit and a non-covalently attached 515-kDa N-terminal subunit. Intracellular domain interacts with MAFB (By similarity). Found in a complex with PID1/PCLI1, LRP1 and CUBNI. Interacts with SNX17, PID1/PCLI1, PDGF and CUBN. The intracellular domain interacts with SHC1, GULP1 and DAB1. Interacts with LRPAP1. Interacts with bacterial exotoxins.

Subcellular Location:
Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm. Nucleus. Note=After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus.

Tissue Specificity:
Most abundant in liver, brain and lung.

Similarity:
Belongs to the LDLR family.
Contains 22 EGF-like domains.
Contains 31 LDL-receptor class A domains.
Contains 34 LDL-receptor class B repeats.

Database links:

Entrez Gene: 4041 Human

Entrez Gene: 16973 Mouse

Entrez Gene: 293649 Rat

Omim: 603506 Human

SwissProt: O75197 Human

SwissProt: Q91VN0 Mouse

Unigene: 6347 Human

Unigene: 274581 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 99久久人人爽亚洲精品美女 | 久久男人av资源站 | 18禁裸乳无遮挡免费网站 | 仙武帝尊动漫在线观看 | 山西太原一级毛片 | 亚洲Av永久无码精品黑人 | 亚洲成亚洲乱码一二三四区软件 | 美女爽到呻吟久久久久 | 国产在线观看精品无码不卡 | 正在播放国产第九十二 | 少妇厨房愉情理伦片视频在线观看 | 国产亚洲精aa成人网站 | 变态视频在线观看 | 免费观看一级欧美片 | 操操影视 | 亚洲精品一区二区三区四区五区 | 99ri精品国产亚洲 | 一区二区三区在线观看免费 | 成年人网站免费 | 麻豆高清 | 色多多网站在线观看 | 久热99视频在线观看 | 日本三级成本人网站 | 亚洲欧美综合在线观看 | 久久精品A一国产成人免费网站 | 亚洲最大无码AV网址 | 午夜寂寞视频无码专区 | 久久久无码精品亚洲日韩 | 操久视频 | 国产精品扒开腿做爽爽的视频 | 欧洲伊人网 | 81精品久久久久久久婷婷 | 小婕子伦流澡到高潮H | 日本精品免费 | 俺去俺来也在线WWW色官网 | av免费在线观看网站 | jvid在线观看 | 人妻暴雨中被强制侵犯在线 | 欧美亚洲国产日韩在线a不卡 | 一本一本久久aa综合精品 | 熟女少妇色综合图区 |