麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
真人一级毛片视频,无翼乌之侵犯工口全彩老师,久久99精品无码一区二区三区
Rabbit Anti-ING4/BF594 Conjugated antibody (bs-10492R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-10492R-BF594
英文名稱 Rabbit Anti-ING4/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的ING4抗體
別    名 Brain my036 protein; Candidate tumor suppressor p33 ING 1 homolog; Candidate tumor suppressor p33 ING-1 homolog; Candidate tumor suppressor p33 ING1 homolog; D6Wsu147e; D6Xrf92; ING 1 like protein; ING 4; ING-1 like protein; ING-4; ING1 like protein; ING4; ING4_HUMAN; Inhibitor of growth family member 4; Inhibitor of growth family member 4 long isoform; Inhibitor of growth protein 4; MGC12557; my036; p29 ING 4; p29 ING-4; p29 ING4; p29ING4; My036; inhibitor of growth protein 4 isoform 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  發(fā)育生物學(xué)  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ING4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008].

Function:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1).

Subunit:
Homodimer. Interacts with H3K4me3 and to a lesser extent with H3K4me2, the interaction augments HBO1 acetylation activity on H3 tails. Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17. Interacts with EP300, RELA and TP53; these interactions may be indirect. Interacts with EGLN1.

Subcellular Location:
Nucleus.

Post-translational modifications:
Citrullination by PADI4 within the nuclear localization signal disrupts the interaction with p53 and increases susceptibility to degradation.

Similarity:
Belongs to the ING family.
Contains 1 PHD-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q9UNL4 human
UniProtKB/Swiss-Prot: Q8C0D7 mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 97人妻免费碰视频碰免 | 亚洲福利视频一区二区 | 日日干干 | 天天艹逼 | 午夜a毛片免费全部播放完整 | 中文字幕亚洲欧美在线不卡 | 亚洲永久精品网站 | 国产人妻无码一区二区三区不卡 | 色综合天天综合网天天看片 | 久久精品2021国产 | 亚洲欧洲精品一区二区三区四区 | 久久午夜精品影院一区 | 久久精品日产第一区二区三区在哪里 | 欧美射射射 | 中文字幕第八页 | 裸体丰满少妇做受久久99精品 | 精品人妻中文av一区二区三区 | 精品视频国产亚洲 | 亚洲国产精品久久久久久久久久久 | 欧美日韩精品久久久 | 91网站网址 | 天天干干干 | 国产美女视频一区二区三区 | 日本在线播放一二三区 | 98k网站毛片成年女人网站 | 亚洲爆乳中文字幕无码专区网站 | 亚洲の无码热の综合 | 天天干夜夜曰 | 欧美成人免费一级 | 欧美人与动牲猛交XXXXBBBB | 国产人人人 | 99热精品只有这里有 | 久久看视频 | 日韩人妻系列无码专区 | 日本亚洲精品一区二区三 | 国产成人精品免费久久久久 | 亚洲AV无码乱码在线观看代蜜桃 | 夜色影视精品一区二区三区18 | 日本高清有码 | 午夜精品乱人伦小说区 | 日本丰满人妻久久久久久久 |