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Rabbit Anti-TPGS1/Gold Conjugated antibody (bs-17165R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-17165R-Gold
英文名稱 Rabbit Anti-TPGS1/Gold Conjugated antibody
中文名稱 膠體金標記的電壓門控離子通道蛋白TPGS1抗體
別    名 C19orf20; two pore segment channel 1; Gene trap ROSA b geo 22; GTRGEO22; PGs1; Tubulin polyglutamylase complex subunit 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TPGS1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
TPCN1 is a widely expressed, 816 amino acid voltage-gated cation channel protein with predominant expression in lung, liver, heart and kidney. In the kidney, TPCN1 localizes to the inner medullary collecting ducts. In contrast with the distantly related four-domain voltage-gated calcium and sodium channels and the more closely related four-domain ion transport protein located on the surface of sperm cells (CatSper), TPCN1 is a two-domain channel. Similar to the four-domain channel structure, each of the two homologous domains that comprise TPCN1 contains six transmembrane segments (S1-S6) with a pore loop between S5 and S6 and a voltage sensor segment that is positively charged. TPCN1 has hydrophilic N- and C-termini that localize to the cytoplasm.

Function:
TPGS1 may act in the targeting of the tubulin polyglutamylase complex. It is required for the development of the spermatid flagellum.

Subunit:
Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1.

Subcellular Location:
Microtubule.

Database links:

Entrez Gene: 91978 Human

Entrez Gene: 110012 Mouse

SwissProt: Q6ZTW0 Human

SwissProt: Q99MS8 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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