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Rabbit Anti-HS3ST3A1/Gold Conjugated antibody (bs-17390R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17390R-Gold
英文名稱 Rabbit Anti-HS3ST3A1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的HS3ST3A1蛋白抗體
別    名 3-OST-3A; 30ST3A1; 3OST3A1; h3 OST 3A; h3-OST-3A; heparan sulfate (glucosamine) 3 O sulfotransferase 3A1; Heparan sulfate 3 O sulfotransferase 3A1; Heparan sulfate 3-O-sulfotransferase 3A1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; HS3SA_HUMAN; HS3ST3A1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HS3ST3A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Jul 2008]

Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney.

Similarity:
Belongs to the sulfotransferase 1 family.

Database links:

Entrez Gene: 9955 Human

GenBank: NM_006042.1 Human

Omim: 604057 Human

SwissProt: Q9Y663 Human

Unigene: 462270 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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