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Rabbit Anti-MNF1/Gold Conjugated antibody (bs-17693R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-17693R-Gold
英文名稱 Rabbit Anti-MNF1/Gold Conjugated antibody
中文名稱 膠體金標記的線粒體類核因子1/乳腺癌相關蛋白SGA-81M抗體
別    名 bA6B20.2; Breast cancer-associated protein SGA-81M; C6orf125; Cbp6; UQCC2_HUMAN; M19; Mitochondrial nucleoid factor 1; Mitochondrial protein M19; MNF1; RP11-6B20.2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MNF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]

Function:
Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells.

Subcellular Location:
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space (By similarity). Mitochondrion matrix (By similarity). Mitochondrion inner membrane (By similarity). Note=Predominantly expressed in the mitochondrial inner membrane (By similarity).

Tissue Specificity:
Pancreas, skeletal muscle, kidney, liver and heart.

Database links:

Entrez Gene: 84300 Human

Omim: 614461 Human

SwissProt: Q9BRT2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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