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Rabbit Anti-TPSG1/Gold Conjugated antibody (bs-12684R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12684R-Gold
英文名稱 Rabbit Anti-TPSG1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的膜類胰蛋白酶1抗體
別    名 gamma I; gamma II; lung tryptase; mast cell protease II; mast cell tryptase; pituitary tryptase; PRSS31; Serine protease 31; skin tryptase; TMT; Tpsg1; Transmembrane tryptase; trpA; TRYG1_HUMAN; Tryptase gamma (EC:3.4.21.-); tryptase gamma 1; tryptase gamma; Tryptase gamma heavy chain; tryptase gamma I; tryptase gamma II; Tryptase gamma light chain.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  泛素  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TPSG1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in many tissues.

Similarity:
Belongs to the peptidase S1 family.
Tryptase subfamily.
Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 25823 Human

Entrez Gene: 26945 Mouse

Entrez Gene: 302990 Rat

Omim: 609341 Human

SwissProt: Q9NRR2 Human

SwissProt: Q9QUL7 Mouse

Unigene: 592076 Human

Unigene: 180108 Mouse

Unigene: 163109 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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