麻豆av资源_日本三级一区_www.狠狠艹_国产精妇在线观看第一区_成人性生交大片免费看中国A片_日本一本久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
国产在线va,国外xxx另类视频,波多野结衣永久免费视频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Lamin B/Gold Conjugated antibody (bs-23709R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23709R-Gold
英文名稱 Rabbit Anti-Lamin B/Gold Conjugated antibody
中文名稱 膠體金標記的核纖層蛋白B抗體(細胞核膜標志物)
別    名 lamin B1; LMB1; LMN; LMN2; LMNB 1; LMNB; LMNB1; MGC111419; LMNB1_HUMAN; Lamin-B1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產(chǎn)品類型 內(nèi)參抗體 
研究領域 細胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導  細胞凋亡  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Lamin B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010].

Function:
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Subunit:
Homodimer. Interacts with lamin-associated polypeptides IA, IB and 2.

Subcellular Location:
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Post-translational modifications:
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.

DISEASE:
Defects in LMNB1 are the cause of leukodystrophy demyelinating autosomal dominant adult-onset (ADLD) [MIM:169500]. ADLD is a slowly progressive and fatal demyelinating leukodystrophy, presenting in the fourth or fifth decade of life. Clinically characterized by early autonomic abnormalities, pyramidal and cerebellar dysfunction, and symmetric demyelination of the CNS. It differs from multiple sclerosis and other demyelinating disorders in that neuropathology shows preservation of oligodendroglia in the presence of subtotal demyelination and lack of astrogliosis.

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 396223 Chicken

Entrez Gene: 4001 Human

Entrez Gene: 16906 Mouse

Entrez Gene: 116685 Rat

Omim: 150340 Human

SwissProt: P14731 Chicken

SwissProt: P20700 Human

SwissProt: P14733 Mouse

SwissProt: P70615 Rat

Unigene: 89497 Human

Unigene: 4105 Mouse

Unigene: 11362 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核膜標志物(Nuclear Envelope Marker)
核纖層蛋白(Lamin) 是緊貼核內(nèi)膜的一層厚度為20~50nm的纖維蛋白層或纖維網(wǎng)絡。核纖層與細胞質(zhì)骨架、核骨架連成一個整體,一般認為核纖層將核被膜和染色質(zhì)提供了結(jié)構(gòu)支架。有學者研究認為:lamin蛋白與細胞凋亡及衰老有關聯(lián),它包括:核纖層蛋白A、核纖層蛋白B、核纖層蛋白C幾個不同亞型的蛋白。
版權(quán)所有 2004-2026 m.jywcc.com 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 看真人视频一级毛片 | 久久精品黄AA片一区二区三区 | 国产伊人色 | 中国一级毛片免费视频 | 四虎精品成人影院观看地址 | 精品视频在线观看一区二区三区 | 中文字幕一区在线播放 | 在线精品亚洲一区二区 | 黄色片aaaaaa | 国产v亚洲v日韩v欧美v片 | 亚洲热热色 | 国产精品亚洲专区无码蜜芽 | 狠狠热免费视频 | 国产尤物精品自在拍视频首页 | 91在线播放?看 | 神偷奶爸4中文版免费观看 91视频在线观看大全 | 又粗又猛又黄又爽无遮挡涩爱 | 欧美一区二区三区的 | 日本在线视频网 | 激情综合婷婷色五月蜜桃 | 成人免费a级毛片无码片在线播放 | 日韩在线播放一区二区三区 | 韩国一级无码免费精品视频 | 歐美性受XXXX黑人XYX性爽 | 苍井优经典三级在线观看 | 国产精品视频一区在线观看 | 日本不卡一区二区三区在线 | 国产91www | 精品国产乱码久久久久久密桃99 | 午夜性刺激免费看视频 | 国产一区二区亚洲 | 老头巨大挺进莹莹的体内免费视频 | 国产精品久久久久久精 | 很污网站| 国产精品一区二区AV蜜芽 | caoporn免费| 久久国产成人午夜av影院宅 | 一级片国产精品三级一区二区三区 | 任你躁久久久久久妇女av | 亚洲一区亚洲 | 福利一区和二区 |